- Format 84 capsules
Content:
– 1 WOMAN box: 56 caps.
– 1 MAN box: 28 caps.
A unique probiotic solution to enhance fertility in couples
With an 89% success rate in restoring microbial balance
Fertibiome®, with its exclusive and patented strain, Ligilactobacillus salivarius PS11610, is a development of the Zendal Group, an international benchmark in biotechnology.
At Zendal, building effective health solutions grounded in robust scientific evidence is a fundamental principle.
- CONTINUOUS INNOVATION
I
PROFEC II CLINICAL TRIAL
The scientific forefront of fertility
Currently under evaluation in the PROFEC II clinical study.
Designed to restore the microbiota and promote a more favorable environment for conception.
Collaborating entities:
Recruiting center
Clinical Trials.gov ID 
NCT06122207 | Sponsor ProbiSearch SL | Information provided by ProbiSearch SL Last Update Posted 2024-02 29 https://clinicaltrials.gov/study/NCT06122207
The Real Impact of Your Microbiota on Fertility
DYSBIOSIS
Approximately 30% of infertility cases are of unknown origin.1
Dysbiosis is a key factor in implantation failure in more than a quarter of women with infertility.2
It is observed in one-third of women undergoing Assisted Reproductive Technology (ART) treatments.3
1 in 6 couples suffers from infertility (WHO); in women with dysbiosis, less than 10% achieve pregnancy.4
EUBIOSIS
Fertibiome® naturally balances your microbiota to increase your chances of achieving pregnancy.
1.Practice Committee of the American Society for Reproductive Medicine. Evidence-based treatments for couples with unexplained infertility: a guideline. Fertil Steril. 2020 Feb;113(2):305-322
2.Moreno et al. Endometrial microbiota composition is associated with reproductive outcome in infertile patients. Microbiome (2022) 10:1
3.Haahr T et al. Vaginal microbiota correlations to gynecological symptoms, intimate hygiene practices, and background parameters of IVF patients: a cross‑sectional study. Journal of Assisted Reproduction and Genetics. 2025 42:3443–3452.
4.Hiratsuka D, et al. The reproductive tract microbiome and female fertility: dysbiosis, disease links, and emerging therapeutic strategies, Fertility and Sterility. 2026. Jan 21:S0015-0282(26)00039-7
5.Chen et al. The relationship between vaginal and endometrial microbiota and the outcome of Frozen-Thawed embryo transfer during hormone replacement cycles. BMC Microbiol. 2025 Aug 11;25(1):494.
Improve Your Fertility with Fertibiome®
Its exclusive and patented strain, Ligilactobacillus salivarius PS11610, has demonstrated the ability to rebalance the endometrium and promote the reversal of dysbiosis in both partners
Restored Internal Balance
Healthy and protected microbiome
Multiply your chances of success
Fertibiome® is safe, well tolerated, clinically tested, and can be incorporated into Assisted Reproduction Technique (ART) protocols without altering standard clinical practice
- CONTINUOUS INNOVATION
I
PROFEC II CLINICAL TRIAL
JOIN THE ADVANCEMENT THAT IS REDEFINING FERTILITY
Currently being conducted jointly in Spain and Portugal
This clinical trial evaluates:
- Pregnancy rates
- Improvement in the uterine inflammatory profile
- Improvement of the uterine microbiome
If you are interested in participating, please complete a short form. Our clinical team will review your application and contact you as soon as possible.
Clinical Trials.gov ID 
NCT06122207 | Sponsor ProbiSearch SL | Information provided by ProbiSearch SL Last Update Posted 2024-02 29 https://clinicaltrials.gov/study/NCT06122207
Clinical Studies Supporting the efficacy of Fertibiome®
88.9%
PROFEC I Study
Developed by Hospital Universitario La Paz, Madrid, 2020
9 out of 10 couples restored microbiota balance. 88.9% after 6 months and 67% within 3 months
Improved uterine immune status with a clear reduction in inflammation.
Reduced urogenital tract dysbiosis in couples, restoring bacterial balance.
Improved embryo implantation, increased pregnancy success, and full-term birth rates in ART couples.
Retrospective Study
Conducted between 09-2021 and 08-2023. Lisbon (Portugal)
694 patients undergoing In Vitro Fertilization (IVF)
IVF evidence: birth success increased from 17.9% to 26.4% with Fertibiome®.
Higher implantation success.
Increase in biochemical pregnancy rates: 42.6% compared to 34%.
26.4%
The clinical evidence obtained confirms the efficacy of Fertibiome® treatment within the framework of Assisted Reproduction Techniques (ART).
How to Take Fertibiome®. Directions for Use
KEEP REFRIGERATED (2–8°C).
Fertibiome® contains one billion Colony Forming Units (CFU). To guarantee preservation, refrigeration is required.
INDICATION
FORMAT
DURATION
Couple
84 capsules
28 days
Woman
84 capsules
1 month and a half
Woman
56 capsules*
28 days
Man
28 capsules*
28 days
* Formats not currently available
GLUTEN-FREE
ORAL ADMINISTRATION
DUAL
Man - Woman
Woman
2 capsules per day
(1 every 12 hours)
Man
1 capsule per day
(1 every 24 hours)
Fertibiome® contributes to improve fertility in couples
Frequently Asked Questions
Can I take Fertibiome® without having performed a dysbiosis test?
Yes, Fertibiome® can be taken without having the results of dysbiosis testing . Fertibiome® is a food supplement that can be taken without a prescription.
Is it safe? Can I experience adverse reactions or side effects?
Fertibiome® contains a strain of the species Ligilactobacillus salivarius, included in the EFSA QPS list, with established safety.
In addition, no adverse reactions related to the intake of Fertibiome® have been reported in couples treated with the product.
If I become pregnant while taking Fertibiome®, should I stop treatment? Does it affect the baby?
In the event of pregnancy, the initiated treatment may be continued without any problems. This helps maintain an optimal microbial composition in the genital tract for a healthy pregnancy. La toma de Fertibiome® intake does not affect the baby’s development.
How long should I take it?
Our studies have shown that taking Fertibiome® for a minimum period of 3 months helps modulate the microbiota, improving the chances of pregnancy. However, a 6-month intake helps consolidate the results, with an 88.9% reduction in dysbiosis achieved at 6 months.
What is the composition of Fertibiome®?
Ligilactobacillus salivarius PS11610 strain
Also contains:
- Maltodextrin
- Coating agent: Hydroxypropyl methylcellulose
- Anti-caking agent: Magnesium stearate
- Black iron oxide
*Vegetarian capsule. Suitable for different lifestyles.
The package leaflet can be downloaded at the following link: Fertibiome
Can I take it if I have allergies or intolerances?
Fertibiome® is suitable for coeliacs (gluten-free).
Fertibiome® is suitable for individuals with lactose intolerance.
Does not contain allergens listed in EU Regulation 1169/2011.
What happens if I forget to take it?
If you forget to take a dose of Fertibiome®, take it as soon as you remember. However, if it is close to the time of your next dose, continue with your regular schedule. Do not take a double dose to make up for a forgotten dose.
Can I take it with other supplements or medications?
In general, probiotics may be taken alongside other supplements and medications; however, it is always advisable to consult a doctor before combining treatments to avoid potential unwanted interactions.
Why does the woman take double the dose compared to the man?
The woman takes 2 capsules daily to modulate the vaginal microbiota. The man takes 1 capsule daily to reverse urogenital tract dysbiosis, preventing the presence of pathogenic microorganisms that may contribute to dysbiosis in the woman. Women have a more abundant microbiota.
Take care of your microbiome and take the first step toward pregnancy
